Leukemia cutis are clinically divided into the specific and nonspecific types. The former demon strates a malignant cell infiltrate on histopathologic examination.
We report a case of leukemia cutis in a 29-year old female which developed specific cutanous manifestations previous to peripheral blood abnormalities, She had suffered from several discrete, bean to walnut sized, tender, erythematous patches and
nodules on the trunk for 3 months and these gradually spread to the right cheek and upper arm. Atypical lymphocytes and incesassed lymphoblasts were notifced on a peripheral blood smear and bone marrow aspiration. A bone marrow biopsy revealed
compact
marrow finding, and increased celluarity. The histopathlogic findings showed diffuse dermal and subcutaneous infiltration of atypical lymphocytes. An immunohistochemical study with kappa, lamda, and leukocyte common antigen(LCA) revealed lymphoid
malignancy, T-cell type.
We treated her with various combined chemotherapy for 2 year, but her skin lesions were not inproved.
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